Bacteriófagos: aliados invisibles en la lucha contra las bacterias resistentes a los antimicrobianos
Bacteriophages: invisibles alies in the fight against antimicrobial resistant bacteria
DOI:
https://doi.org/10.29105/cienciauanl29.138-3Palabras clave:
bacteriófagos, fagoterapia, resistencia antimicrobiana, bacterias resistentes, alternativas terapéuticas, bacteriophages, phage therapy, antimicrobial resistance, resistant bacteria, therapeutic alternatives.Resumen
Debido al aumento de bacterias resistentes a los antibióticos y a las dificultades del desarrollo de nuevos fármacos de este tipo, actualmente se incentiva a la comunidad científica la búsqueda de tratamientos alternativos, entre las cuales resurge la fagoterapia. Los bacteriófagos son virus que infectan bacterias, que pueden replicarse y eliminar a sus hospederos mediante ciclos líticos, un mecanismo con el que desde hace décadas se ha planteado el potencial de estas partículas. Este artículo expone aspectos básicos de los bacteriófagos, revisa los avances actuales en cuanto a su aplicación y analiza ventajas y limitaciones de su uso terapéutico.
Abstract
Due to the increasing prevalence of antibiotic-resistant bacteria and the challenges associated with developing new antibiotics, the scientific community is currently encouraged to explore novel therapeutic alternatives, among which phage therapy has re-emerged. Bacteriophages are viruses that infect bacteria and can replicate and eliminate their hosts through lytic cycles, a mechanism that has been recognized for decades as holding significant therapeutic potential. This article presents the fundamental aspects of bacteriophages, reviews recent advances in their application, and analyzes the advantages and limitations of their therapeutic use.
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Derechos de autor 2026 José M. García-Pérez, Gloria M. González, Gerardo García González
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
